Join us in pioneering life-changing technology

The Role
We’re hiring a Biointerface Engineer (Neural Interfaces / Tissue Engineering / Cell Engineering) to own the design and development of the biological interface layer of our neural systems. This role is responsible for the electrode–tissue interface as a complete system, spanning cells, materials, and integration with hardware. You will define how our devices interface with the body, from in vitro systems through in vivo validation. This is not a narrow cell engineering role. It sits at the intersection of tissue engineering, neural interfaces, and device integration.You will be working closely with our multi-disciplinary team of electrical engineers, materials scientists, neuroengineers, and operators in our Palo Alto lab.

‍What You’ll Do
- Own the design of the biointerface layer, including cells, scaffolds, and material systems that connect device to tissue
- Develop and optimize cell strategies including: primary cell culture, stem-cell-derived systems
- Optimize cell strategies with long-term clinical and regulatory pathways 
- Design and evaluate cell–material interfaces (e.g., hydrogels, ECM coatings etc) to improve integration, stability, and signal quality
- Build and run in vitro interface models to characterize coupling between biology and electronics
- Partner closely with electrical and device teams to optimize signal quality, impedance, and interface performance
- Work with in vivo teams to translate in vitro systems into implantable, testable constructs
- Define and document protocols for reproducible cell culture, interface fabrication, and experimental workflows
- Drive iterative development across the loop: interface design → implantation → signal → failure mode → redesign
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What We’re Looking For
- Experience with cell engineering or genetic manipulation techniques (e.g., CRISPR, viral transduction) where relevant
- Strong hands-on experience in mammalian cell culture (primary cells, stem cells. or differentiated systems)
- Strong background in tissue engineering, bioengineering, neuroscience, or related disciplines
- Experience with in vitro electrophysiology techniques or electrically active cell systems
- Experience in developing and optimising cell–material interfaces (e.g., hydrogels, ECM, coatings)
- Experience designing and running in vitro assays to evaluate biological–electrical interface performance
- Ability to lead projects independently while working in a highly collaborative environment
- Strong communicator with ability to document protocols and drive reproducible experimental workflows
- PhD in Bioengineering, Molecular Biology, Neuroscience, or a related field or equivalent industry experience
- Ability to think at the system level across biology, materials, and device integration

‍Nice to Have
- Familiarity with microfluidics, hydrogel substrates, or implantable systems
- Experience with translational cell therapies
- Animal handling and surgery experience 
- Familiar with in vivo electrophysiology 
- Experience integrating biological systems with devices or materials
- Previous work with startup or interdisciplinary R&D environments
- Understanding of regulatory-minded workflows (GLP, FDA-facing studies)
- Basic data analysis skills (Python, MATLAB, ImageJ, etc.)
- Experience working across in vitro to in vivo translation

Salary/Pay Range
Competitive salary + equity + benefits. Individual pay is determined by several factors, including job-related skills, experience, and relevant education or training.

Benefits
- Competitive salary and equity
- Medical, dental and vision
- Flexible vacation and company-paid holidays
- Healthy meals and snacks provided for non-remote employees
- Paid parental, jury duty, bereavement, family care and medical leave
- 401(k)

‍Why Join Us
At Axo Neurotech, you’ll be joining a team that believes in bold ideas, scientific rigor, and the power of interdisciplinary collaboration. We’re creating the tools that will define the future of neurotechnology - and we’re just getting started.

The Role
We are hiring a Neuroengineer – Neural Systems & Clinical Translation to own signal validation, preclinical execution, and the path from early data to clinical and commercial impact.

This role is responsible for translating device and biointerface designs into quantitative, system-level performance data, and ensuring that what we build produces and generates; recording and stimulating signals that are interpretable, reproducible, and clinically meaningful.

You will own the strategy for demonstrating that our system works, and for structuring the evidence required for regulatory and go-to-market success.

‍What You’ll Do
- Own experimental design across in vitro and in vivo systems
- Lead in vivo electrophysiology studies 
- Define and implement signal validation frameworks (SNR, stability, repeatability, functional relevance)
- Analyze neural data and translate it into actionable system-level insights
- Drive the iteration loop across teams: device → interface → implant → signal → redesign
- Identify failure modes across biology, device, and signal, and design experiments to systematically de-risk them
- Establish reproducible preclinical protocols and data pipelines
- Define the preclinical → clinical translation strategy, including what data is required to advance
- Support and participate in FDA-facing strategy and interactions, including framing study design and results
- Ensure all experiments generate decision-driving data
- Interface with external partners (CROs, surgeons, advisors) to execute studies and refine approach
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What We’re Looking For
- Strong background in neural engineering, bioengineering, or applied neuroscience
- Hands-on experience with in vivo electrophysiology (recording and/or stimulation)
- Experience designing and executing animal studies (rodent required; large animal a plus)
- Ability to think in terms of systems and signal chains.
- Ability to connect signal → function → clinical outcome
- Experience with neural signal processing, statistical inference, and development of decoding/encoding algorithms (Python, MATLAB, or similar)
- Strong experimental rigor with focus on quantitative validation and reproducibility
- Ability to operate across disciplines and collaborate with biology, materials, and hardware teams
- Strong communication skills for documenting, presenting, and framing results for technical and non-technical audiences
- Strong intuition for extracting meaningful biological and functional insights from noisy neural datasets

PhD in Neural Engineering, Biomedical Engineering, Neuroscience, or related field, or equivalent industry experience preferred

‍Nice to Have
- Experience with implantable neural devices 
- Experience with closed-loop or bidirectional neural systems
- Familiarity with computational modeling for neural stimulation
- Familiarity with regenerative medicine and/or novel genetically-targeted techniques
- Exposure to translational or clinical programs
- Exposure to FDA or regulatory processes, including preclinical study design, translational planning, GLP, GCP, or ISO 14155 environments
- Experience working with CROs or external research partners
- Surgical experience or close collaboration with surgical teams

Salary/Pay Range
Competitive salary + equity + benefits. Individual pay is determined by several factors, including job-related skills, experience, and relevant education or training.

Benefits
- Competitive salary and equity
- Medical, dental and vision
- Flexible vacation and company-paid holidays
- Healthy meals and snacks provided for non-remote employees
- Paid parental, jury duty, bereavement, family care and medical leave
- 401(k)

‍Why Join Us
At Axo Neurotech, you’ll be joining a team that believes in bold ideas, scientific rigor, and the power of interdisciplinary collaboration. We’re creating the tools that will define the future of neurotechnology - and we’re just getting started.

The Role
We’re seeking a mission-driven Electrical Engineer to build core data acquisition and test electronics and firmware for our next gen neural interface systems. You will own the bring-up and firmware development of analog acquisition hardware, stimulation circuits, wireless data transfer, and power delivery – working closely with biologists and microfabrication engineers. This role is based in Palo Alto and offers the opportunity to shape foundational technology in a fast-moving, multidisciplinary team.

What You’ll Do
- Build and optimize wireless data and power transfer systems
- Lead PCB schematic, layout, fabrication, assembly and bring-up of custom boards
- Architect unit and system-level testing and debugging across electronics and biointerfaces
- Collaborate cross-functionally with biology and engineering teams 
- Design and build automated electrical test systems for characterizing implant performance under simulated physiological conditions (saline environments, temperature cycling, accelerated aging)
- Develop comprehensive test protocols for neural recording/stimulation electronics, power systems, and wireless telemetry in biologically relevant conditions
- Create scalable test fixtures and benchtop setups that enable rapid iteration and parallel testing of multiple device variants
- Build automated test reporting and data analysis pipelines to track device performance over time

What We’re Looking For
- 5+ years experience developing implantable medical electronics or consumer electronics
- Proficiency with embedded system architecture and board-level bring-up, including RTOS-based firmware, low-power design, peripheral driver development, hardware/software debugging, and common wired/wireless communication protocols such as SPI, I²C, UART, USB, CAN, BLE, and Wi-Fi. 
- Track record of shipping production firmware in C/C++ and/or HDL designs in Verilog/SystemVerilog, from implementation and debugging through validation and deployment. 
- Proficiency in PCB design tools (e.g., Altium, KiCAD) 
- Experience with wireless power/data (e.g., inductive coupling, BLE, RF design)
- Strong understanding of electrical engineering fundamentals, signal integrity, EMI mitigation
- Comfortable with design of high speed digital interfaces
- Experience with testing automation
- Experience working with power and size constrained production products
- Comfortable leading the charge in a hands-on, fast-paced startup environment

Nice to Have
- Background in neurotechnology, bioinstrumentation, or medical device design
- Familiarity with industry standards related to medical devices e.g. IEC 60601
- Experience with electrophysiology recordings
- Expert with FPGA and HDL-based development ([System]Verilog)
- MS or PhD in Electrical Engineering or a related field

Salary/Pay Range
Competitive salary + equity + benefits. Individual pay is determined by several factors, including job-related skills, experience, and relevant education or training.

Benefits
- Competitive salary and equity
- Medical, dental and vision
- Flexible vacation and company-paid holidays
- Healthy meals and snacks provided for non-remote employees
- Paid parental, jury duty, bereavement, family care and medical leave
- 401(k)

‍Why Join Us
At Axo Neurotech, you’ll be joining a team that believes in bold ideas, scientific rigor, and the power of interdisciplinary collaboration. We’re creating the tools that will define the future of neurotechnology - and we’re just getting started.

The Role
We’re always looking for exceptional students and early-career researchers who want to push the boundaries of neuroscience, biology, and engineering. If you’re excited to work at the intersection of living systems and advanced technology, we want to hear from you.

‍Eligibility Requirements
- Currently enrolled in or recently graduated from a degree program (BS, MS, or PhD)
- Field of study: biology, bioengineering, neuroscience, electrical engineering, mechanical engineering, computer science, or related
- Must be authorized to work in the U.S.
- Minimum 12-week commitment, full-time.

‍What You’ll Get
- Hands-on experience with cutting-edge research and development
- Mentorship from experienced engineers and scientists
- Exposure to next gen neural interface design and testing
- Opportunities to contribute to meaningful projects impacting real patients

‍Why Join Us
At Axo Neurotech, you’ll be joining a team that believes in bold ideas, scientific rigor, and the power of interdisciplinary collaboration. We’re creating the tools that will define the future of neurotechnology - and we’re just getting started.

Didn’t find what you were looking for? Tell us what role you would be perfect for, and what you could achieve.

‍Why Join Us
At Axo Neurotech, you’ll be joining a team that believes in bold ideas, scientific rigor, and the power of interdisciplinary collaboration. We’re creating the tools that will define the future of neurotechnology - and we’re just getting started.